In Minnesota, there are three described species within the genus Xenoglossa. All three species nest in the ground, have solitary nests, and are oliogolectic; two specialize on Cucurbita (pumpkin and squash) pollen and the third specializes on Dalea purpurea (purple prairie clover). Xenoglossa pruinosa was formerly in the genus Peponapis, then was placed in the genus Eucera, and most recently moved to Xenoglossa. Xenoglossa albata was formerly assigned to the genera Eucera and Tetraloniella.

Xenoglossa are robustly-shaped, covered in thick hairs, and have broad abdomens. Xenoglossa pruinosa has a protruding clypeus and prominent hair bands on the abdomen. Larger than Xenoglossa pruinosa, Xenoglossa kansensis has light yellow or white markings on the clypeus and mandibles, and rusty-brown legs. Males have very long antennae; females have oval tegulae and collect pollen on long hairs on their hind leg tibia and basitarsus. Bees in this genus range in length from 11 to 16 mm (0.43 to 0.63 inches).